Medical Dynamic

Neuro Oncology：Combined chemotherapy can significantly improve the treatment of fatal brain cancer

The addition of temozolomide (TMZ) to surgical and radiation treatment has been the major improvement in glioblastoma treatment over the past 20years, raising two-year survival...

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Transfer of miRNA in macrophages-derived exosomes induces drug resistance of pancreatic adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is known for its resistance to gemcitabine, which acts to inhibit cell growth by termination of DNA replication. Tumor-associated macrop...

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FAM83A is amplified and promotes cancer stem cell-like traits and chemoresistance in pancreatic cancer

AbstractCancer stem cells (CSCs), also known as tumor-initiating cells (TICs), contribute to tumorigenesis, resistance to chemoradiotherapy and recurrence in human cancers, suggesting targeting CSCs m...

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